Effect Of Orange Red Extract To Interferon Gamma Levels In Hyperglycemic White Rat

Authors

  • Sherly Intanwati Fakultas Kedokteran, Universitas Ciputra
  • William Sayogo Fakultas Kedokteran, Universitas Ciputra

DOI:

https://doi.org/10.30994/jgrph.v5i1.151

Keywords:

Red orange extract, hyperglycemia, IFN-γ

Abstract

Red orange extract is an important component of what is called the Mediterranean diet and they have been used by traditional medicine for their protective health properties, especially to cure sore throats and coughs, showing interesting anti-inflammatory activity. The aim of this study was to evaluate the immuno modulation activity of red orange extract (Citrus sinensis variety: Moro, Tarocco, Sanguinello), which contained anthocyanins, flavanones, hydroxycinnamic acid and ascorbic acid, in mice with hyperglycemia. The results of this study indicated that the administration of red orange extract increased the expression of gamma interferon (IFN-γ) in hyperglycemic white rats. IFN-γ had an important role in enhancing the phagocytic function of macrophages.

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Published

2020-08-04

How to Cite

Intanwati, S., & Sayogo, W. (2020). Effect Of Orange Red Extract To Interferon Gamma Levels In Hyperglycemic White Rat . Journal of Global Research in Public Health, 5(1). https://doi.org/10.30994/jgrph.v5i1.151

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Section

Articles